Dr. Fitzgerald has conducted primary research on dietary and lifestyle interventions that influence both gene expression and epigenetic clocks. As the thinking around biological age assessment continues to evolve and expand, find out what her latest recommendations are for biological age assessment including third generation epigenetic clocks as well as non DNA methylation-based assessments. Discover the specific parts of her multimodal intervention that appear to be statistically most influential on moving the needle on DNA methylation and epigenetic age. Not least, understand the promise of epigenetics more broadly, such as what can be revealed in the placental methylome and how epigenetic signatures can identify early-stage cancer.

Session Learning Objectives:

1.) Review the current state of measuring biological age with an eye towards applications in clinical practice.

2.) Explore emerging clocks: universal pan-mammalian and PCR2 clocks and if scientists are capturing the phenomenon of aging?

3.) Discuss the influence of diet and lifestyle on epigenetics more broadly and the emergence of an entire new field of science devoted to these investigations.

4.) Examine key nutrients that favorably influence the epigenome, clocks, and beyond. 

5.) Identify the most appropriate and affordable epigenetic age measurements for clinical practice.                                   

6.) Understand emerging bio age clocks and their underlying mechanisms, including the entire DNA methylome.             

7.) Explore the promise of epigenetic tools, such as the placental methylome, for identifying early cancer signatures.       

8.) Discuss recent research findings on specific nutrients that influence the bio.

9.) Assess the age/epigenetic clock in slowing down epigenetic aging.